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Old 04-30-2009, 03:45 PM
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Default Does anyone know why hospitals now refuse to give the medication ONDANSETRON/ZOFRAN, for hyperemesis ?

I had hyperemesis when I had both my kids, the first time 5 years agao, the hospital prescribed this to me to ease the sickness, it worked brilliantly, I had to take it right up until my son was born........last year when i was in hospital with hyperemesis with my second child, they refused to prescribe but wouldnt give a reason as to why,
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Old 04-30-2009, 03:45 PM
DESCOMBES

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simplu benifit vs risk situtaion your case doesnot need such strong medicine
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Old 04-30-2009, 03:46 PM
Sposato

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well I cannot speak to your particular hospital or situation, but I can tell you why several hospitals I worked in did stop using Zofran. First, because a nurse must be trained to administer it correctly, there is a procedure involved, not following the procedure can result in some pretty nasty side effects, the time and cost involved in using this drug is prohibitive.

Second, there have been some fatal side effects to zofran that are not typically found in other anti-emetics so it is not a good risk, drives up the cost of liability insurance.

Third, it was never intended for anything other than as an adjuct to chemo therapy induced nausea and vomiting.

So while it probably did work well for you, your outcome was a lucky one, not a typical one.
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Old 04-30-2009, 03:46 PM
Omondi

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Zofran initially only had a licence for nausea and vomiting following cytotoxic therapy. This was later extended to cover post operative nausea and vomiting. It has never had a licence for hyperemesis gravidarum, the sickness of pregnancy. Its data sheet in fact precludes its use in pregnancy and during breast feeding!
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Old 04-30-2009, 03:46 PM
HOOPER

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use of ondansetron in patients following abdominal surgery may mask a progressive ileus and/or gastric distention
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