i've heard that this medicine does not work and it induces cardiac problem. is it true?

The trial failed to show that Zetia was more effective than simvastatin (generic Zocor) alone. This is the first trial for its effectiveness. There is also some evidence that the drug companies involved MAY have delayed the release of the trial.



It was NOT designed to prove or disprove the belief that cholesterol is a risk factor in coronary disease.



"From this we can also conclude that lowering LDL does not reduce atheroclerosis progression or coronary events."



That's a bit of a stretch. ONE study that was not even designed to prove the above statement.

The results of the ENHANCE trial show that zetia is useless at reducing the progression of atheroslerosis and preventing coronary events, despite the fact that it lowered LDL. From this we can also conclude that lowering LDL does not reduce atheroclerosis progression or coronary events. I dont't think, statisticaly, it can be said to be unsafe. There are rumours that further trials are showing this, but as far as I know no data has been released to confirm this.

for the lowdown on cholesterol

http://cholesterolwise.bravehost.com/

Is a prescription medicine Zetia that a person works with existing legislation whether healthy food and other cholesterol drugs are, bad cholesterol reduction. It is safe because of his heart disease and heart attack risk than cholesterol, which clogs arteries due lowers.

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I think it is safe.
Nothing heard about it's side effects yet.

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In December 2007, the New York Times published an article entitled "Data about Zetia risk was not fully revealed." The article claimed that Merck and Schering-Plough, the manufacturers of Zetia (aka ezetimibe), have information pertaining to the risk of liver damage when taking this cholesterol lowering medication in combination with statin drugs but that the companies have not released them to the public. The 2 companies confirm that this information exists yet justify not publishing...

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A recent clinical trial on the bad cholesterol-lowering drug Zetia was stopped early after scientists found that a combination of this drug and a statin was less effective at reducing cholesterol buildup in the arteries than a combo of a statin and Niaspan, a drug that raises good cholesterol. Experts say this study shows clear evidence that using niacin drugs such as Niaspan to raise good cholesterol in combination with a statin is a superior treatment to adding Zetia to standard statin treatment.

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oh, so zetia is really not suitable for intake anymore?

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^it can be as long as your doctor has prescribed it to you after a thorough check up and analysis. Here are some more Zetia side effects:
Diarrhea; dizziness; headache; joint pain; sinus inflammation; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur when using Zetia:
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; dark urine; depression; fever, chills, or persistent sore throat; numbness or tingling of the skin; severe or persistent joint pain; severe stomach or back pain with nausea and vomiting; unexplained muscle pain, tenderness, or weakness; yellowing of the eyes or skin.

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